ABCB7 Polyclonal Antibody | G-AB-08775

ABCB7 Polyclonal Antibody | G-AB-08775 | Gentaur Antibodies

Overview: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X) (q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Category Type: Polyclonal Antibody

Research Areas: Metabolism, Signal Transduction, Stem Cells

Synonyms: ABCB7, ABC7, ASAT, Atm1p, EST140535

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 22

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ABCB7 (NP_004290.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O75027

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ABCB7 Polyclonal Antibody DataSheet