Recombinant Protein

 

 

E. coli expressed proteins form Gentaur

 

CAS lab uses several up to 4 purification steps to purify our recombinants.

chemistry-lab-shallow-dof-2021-09-01-00-22-52-utc-2-.jpg

Escherichia coli produces recombinant proteins.

This cell factory used for the synthesis of recombinant proteins in E. coli and plasmids.

Recombinant proteins whare first made by Peprotec Ltd. that took the gene of interest, cloned it in whatever expression vector then, the proteins where ready for HPLC purification and characterization by cell culture.

Peprotech did not make all the recombinants themselves. They exchanged most of the cytokines in their catalog with other researchers. Int his way having some proteins they made the biggest catalog available in 1997.

In practice, however, lots of factors can go wrong. Poor growth of the host, inclusion body (IB) formation, protein inactivity, and even not obtaining any protein at all. Glycosilation is better in Pychia or CHO recombinants than in proteins from E. Coli expression.

CAS Lab is a leader in dealing with difficult-to-express proteins.

Inclusion bodies (IBs), protein aggregates inside of the cytoplasm of the cell publication by C Slouka.

  • Recombinant Human B-lymphocyte antigen CD20 (MS4A1) - VLPs (Active) Recombinant Human B-lymphocyte antigen CD20 (MS4A1) - VLPs (Active)
    Gentaur Recombinants

    Recombinant Human B-lymphocyte antigen CD20 (MS4A1) - VLPs (Active)

    Recombinant Human B-lymphocyte antigen CD20 (MS4A1) - VLPs (Active) in Stock Available in 3-7 business days. Research Areas: Cancer Uniprot NO: P11836 Gene Names: MS4A1 Species: Homo sapiens (Human) Source: Mammalian cell Expression Region:...
    $471 - $4,027
  • Recombinant Human C-C chemokine receptor type 8 (CCR8) - VLPs (Active) Recombinant Human C-C chemokine receptor type 8 (CCR8) - VLPs (Active)
    Gentaur Recombinants

    Recombinant Human C-C chemokine receptor type 8 (CCR8) - VLPs (Active)

    Recombinant Human C-C chemokine receptor type 8 (CCR8) - VLPs (Active) in Stock Available in 3-7 business days. Research Areas: Cancer Uniprot NO: P51685 Gene Names: CCR8 Species: Homo sapiens (Human) Source: Mammalian cell Expression Region:...
    $471 - $2,447
  • Recombinant Human Claudin-18.2(CLDN18.2)-VLPs (Active) Recombinant Human Claudin-18.2(CLDN18.2)-VLPs (Active)
    Gentaur Recombinants

    Recombinant Human Claudin-18.2 (CLDN18.2)-VLPs (Active)

    Recombinant Human Claudin-18.2 (CLDN18.2)-VLPs (Active) in Stock Available in 3-7 business days. Research Areas: Cancer Uniprot NO: P56856 Gene Names: CLDN18.2 Species: Homo sapiens (Human) Source: Mammalian cell Expression Region: 1-261aa Sequence:...
    $396 - $3,311
  • Recombinant Enterokinase
    Gentaur

    Recombinant Enterokinase

    Recombinant Enterokinase Description: Recombinant Enterokinase (rEK) is a highly purified preparation of the catalytic subunit of bovine enterokinase, a serine protease which recognizes the identical cleavage site as the native enzyme (AspAspAspAspLys↓)...
    $605
  • Recombinant Human IL-13
    Gentaur

    Recombinant Human IL-13

    Recombinant Human IL-13 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $589
  • Recombinant Human IL-12
    Gentaur

    Recombinant Human IL-12

    Recombinant Human IL-12 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $631 - $1,094
  • Recombinant Human IL-17
    Gentaur

    Recombinant Human IL-17

    Recombinant Human IL-17 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $421
  • Recombinant Human IL-18
    Gentaur

    Recombinant Human IL-18

    Recombinant Human IL-18 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463
  • Recombinant Human IL-8
    Gentaur

    Recombinant Human IL-8

    Recombinant Human IL-8 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463
  • Recombinant Human IL-3
    Gentaur

    Recombinant Human IL-3

    Recombinant Human IL-3 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463
  • Recombinant Human TGF-β1
    Gentaur

    Recombinant Human TGF-β1

    Recombinant Human TGF-β1 Description: Human TGFβ1 (GenBank Accession No. NM_000660), amino acids 30-390 (end) with Cys33Ser mutation and N-terminal His-tag, disulfide-linked homodimers of TGFβ1 LAP and mature TGFβ1, MW= ~75kDa and 25kDa, under...
    $431
  • Recombinant Human M-CSF
    Gentaur

    Recombinant Human M-CSF

    Recombinant Human M-CSF Description: M-CSF (Macrophage colony-stimulating factor, CSF-1) is a survival factor essential for the proliferation and development of monocytes, macrophages, and osteoclast progenitor cells. M-CSF also induces VEGF (vascular...
    $463
  • Recombinant Human BFGF
    Gentaur

    Recombinant Human BFGF

    Recombinant Human BFGF Description: Human basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. bFGF has been shown to...
    $325
  • Recombinant Human EGF
    Gentaur

    Recombinant Human EGF

    Recombinant Human EGF Description: Recombinant human epidermal growth factor is 6.2kDa globular protein comprosed of 53 amino acids. EGF is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal and epithelial cells...
    $253
  • Recombinant Human PDGF-BB
    Gentaur

    Recombinant Human PDGF-BB

    Recombinant Human PDGF-BB Description: PDGF-BB is a mitogen initially identified as simian sarcoma viral oncogene homolog. It belongs to the PDGF family which includes five members, PDGF-AA, PDGF-BB, PDGF-AB, PDGFCC, and PDGF-DD. PDGF-AA, AB, and BB...
    $421
  • Filgrastim (rHuG-CSF)
    Gentaur

    Filgrastim (rHuG-CSF)

    Filgrastim (rHuG-CSF) Description: Filgrastim is a recombinant human granulocyte colony stimulating factor (rHuG-CSF), produced by recombinant DNA technology using E.coli. It is a 175 amino acid protein, non-glycosylated, and has a molecular weight of...
    $328 - $376
  • Molgramostim (rHuGM-CSF)
    Gentaur

    Molgramostim (rHuGM-CSF)

    Molgramostim (rHuGM-CSF) Description: Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF) was initially characterized as a factor that can support the in vitro colony formation of granulocyte macrophage progenitors. It is also a growth factor for...
    $315 - $411
  • Recombinant Mouse GM-CSF
    Gentaur

    Recombinant Mouse GM-CSF

    Recombinant Mouse GM-CSF Description: Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF) was initially characterized as a factor that can support the in vitro colony formation of granulocyte macrophage progenitors. It is also a growth factor for...
    $421 - $883
  • Recombinant Human IFN-γ
    Gentaur

    Recombinant Human IFN-γ

    Recombinant Human IFN-γ Description: Interferon gamma (IFN-γ) is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by...
    $325 - $463
  • Recombinant Human IFN α-2b
    Gentaur

    Recombinant Human IFN α-2b

    Recombinant Human IFN α-2b Description: Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon...
    $325 - $463
  • Recombinant Human IFN α-2a
    Gentaur

    Recombinant Human IFN α-2a

    Recombinant Human IFN α-2a Description: Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon...
    $325 - $463
  • Recombinant Human IL-33
    Gentaur

    Recombinant Human IL-33

    Recombinant Human IL-33 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463 - $1,072
  • Recombinant Human IL-21
    Gentaur

    Recombinant Human IL-21

    Recombinant Human IL-21 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463 - $1,094
  • Recombinant Human IL-7
    Gentaur

    Recombinant Human IL-7

    Recombinant Human IL-7 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463 - $1,072
  • Recombinant Human IL-1 alpha
    Gentaur

    Recombinant Human IL-1 alpha

    Recombinant Human IL-1 alpha Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be...
    $463 - $1,072
  • Recombinant Human IL-15
    Gentaur

    Recombinant Human IL-15

    Recombinant Human IL-15 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463 - $1,072
  • Recombinant Human IL-6
    Gentaur

    Recombinant Human IL-6

    Recombinant Human IL-6 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $395 - $1,072
  • Recombinant Human IL-2
    Gentaur

    Recombinant Human IL-2

    Recombinant Human IL-2 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $325 - $463
  • Recombinant Human IL-4
    Gentaur

    Recombinant Human IL-4

    Recombinant Human IL-4 Description: The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided...
    $463 - $1,094
  • Recombinant Human SCF
    Gentaur

    Recombinant Human SCF

    Recombinant Human SCF Description: SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to...
    $463 - $1,072
  • Recombinant Human TNF-α
    Gentaur

    Recombinant Human TNF-α

    Recombinant Human TNF-α Description: TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells, including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands, and...
    $390 - $463