ACTN1 Monoclonal Antibody | G-AB-05608

ACTN1 Monoclonal Antibody | G-AB-05608 | Gentaur Antibodies

Overview: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Category Type: Monoclonal Antibody

Research Areas: Cancer, Developmental Biology, Signal Transduction, Stem Cells

Synonyms: actinin 1 smooth muscle, Actinin alpha 1, actinin, alpha 1, ACTN 1, Actn1, ACTN1, Alpha Actinin 1, Alpha actinin cytoskeletal isoform, Alpha-actinin cytoskeletal isoform, Alpha-actinin-1, BDPLT15, F actin cross linking protein, F-actin cross-linking protein, FLJ40884, FLJ54432, Non muscle alpha actinin 1, Non-muscle alpha-actinin-1

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Gene ID:

Accession #:

Clonality: Monoclonal

Immunogen: Recombinant Protein of a-actinin of ACTN1

Clone #: Clone:1D4

Conjugation: Unconjugated

Swissprot: P12814

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Protein A purification

Application: IHC-p

Dilution: IHC 1:100-200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ACTN1 Monoclonal Antibody DataSheet