AGXT Polyclonal Antibody | G-AB-01407

AGXT Polyclonal Antibody | G-AB-01407 | Gentaur Antibodies

Overview: Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1) , also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: AGT, AGT1, Agxt, AGXT1, Alanine glyoxylate aminotransferase, Alanine glyoxylate aminotransferase3, Alanine--glyoxylate aminotransferase, EC 2.6.1.44, EC 2.6.1.51, Hepatic peroxisomal alanine glyoxylate aminotransferase, Hepatic peroxisomal alanine:glyoxylate aminotransferase, L alanine glyoxylate aminotransferase 1, MS773, PH1, Serine pyruvate aminotransferase, Serine--pyruvate aminotransferase, Serine--pyruvate aminotransferase, mitochondrial, Serine:pyruvate aminotransferase, SPAT, SPT, SPYA, TLH6

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000021

Clonality: Polyclonal

Immunogen: Synthetic peptide of human AGXT

Clone #:

Conjugation: Unconjugated

Swissprot: P21549

Santa Cruz: sc-167057

Calculated MW: 43 kDa

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AGXT Polyclonal Antibody DataSheet