AKAP5 Polyclonal Antibody | G-AB-11146

AKAP5 Polyclonal Antibody | G-AB-11146 | Gentaur Antibodies

Overview: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: AKAP5, AKAP75, AKAP79, H21

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9495

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human AKAP5 (NP_004848.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: P24588

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AKAP5 Polyclonal Antibody DataSheet