AKTIP Polyclonal Antibody | G-AB-10993

AKTIP Polyclonal Antibody | G-AB-10993 | Gentaur Antibodies

Overview: The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB) /Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: AKTIP, FT1, FTS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 64400

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human AKTIP (NP_071921.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H8T0

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AKTIP Polyclonal Antibody DataSheet