ALDOB Polyclonal Antibody | G-AB-10366

ALDOB Polyclonal Antibody | G-AB-10366 | Gentaur Antibodies

Overview: Fructose-1, 6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1, 6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: ALDOB, ALDB, ALDO2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 229

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ALDOB (NP_000026.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P05062

Santa Cruz:

Calculated MW: 39 kDa

Observed MW: 39 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:1000-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ALDOB Polyclonal Antibody DataSheet