ANPEP Polyclonal Antibody | G-AB-10764

ANPEP Polyclonal Antibody | G-AB-10764 | Gentaur Antibodies

Overview: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology, Stem Cells

Synonyms: ANPEP, APN, CD13, GP150, LAP1, P150, PEPN

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 290

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ANPEP (NP_001141.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P15144

Santa Cruz:

Calculated MW: 109 kDa

Observed MW: 180 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ANPEP Polyclonal Antibody DataSheet