APBB1 Polyclonal Antibody | G-AB-09844

APBB1 Polyclonal Antibody | G-AB-09844 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP) , transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: APBB1, FE65, MGC:9072, RIR

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 322

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human APBB1 (NP_663722.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O00213

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

APBB1 Polyclonal Antibody DataSheet