APLP2 Polyclonal Antibody | G-AB-10665

APLP2 Polyclonal Antibody | G-AB-10665 | Gentaur Antibodies

Overview: This gene encodes amyloid precursor- like protein 2 (APLP2) , which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: APLP2, APLP-2, APPH, APPL2, CDEBP

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 334

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human APLP2 (NP_001135750.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q06481

Santa Cruz:

Calculated MW: 59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa

Observed MW: 87 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

APLP2 Polyclonal Antibody DataSheet