APP Polyclonal Antibody | G-AB-07465
Gentaur Antibodies
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Gentaur Antibodies
APP Polyclonal Antibody | G-AB-07465
- SKU:
- G-AB-07465
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
APP Polyclonal Antibody | G-AB-07465 | Gentaur Antibodies
Overview: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy) . Multiple transcript variants encoding several different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Neuroscience
Synonyms: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4, APP, Aβ42, preA4
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 351
Accession #:
Clonality:
Immunogen: A synthetic peptide of human APP (NP_000475.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P05067
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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