ARRB1 Polyclonal Antibody | G-AB-07283

ARRB1 Polyclonal Antibody | G-AB-07283 | Gentaur Antibodies

Overview: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: ARRB1, ARB1, ARR1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 408

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ARRB1 (NP_004032.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P49407

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:20-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ARRB1 Polyclonal Antibody DataSheet