ASC / TMS1 Polyclonal Antibody | G-AB-07605

ASC / TMS1 Polyclonal Antibody | G-AB-07605 | Gentaur Antibodies

Overview: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD) . The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: PYCARD, ASC, CARD5, TMS, TMS-1, TMS1, PYD and CARD domain containing, ASC / TMS1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 29108

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ASC / TMS1 (NP_037390.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9ULZ3

Santa Cruz:

Calculated MW: 15 kDa/19 kDa/21 kDa

Observed MW: 22 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ASC / TMS1 Polyclonal Antibody DataSheet