ASCC1 Polyclonal Antibody | G-AB-09218

ASCC1 Polyclonal Antibody | G-AB-09218 | Gentaur Antibodies

Overview: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1) , nuclear factor kappa-B (NF-kB) and serum response factor (SRF) . The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: ASCC1, ASC1p50, CGI-18, SMABF2, p50

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 51008

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ASCC1 (NP_001185727.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q8N9N2

Santa Cruz:

Calculated MW: 41 kDa/45 kDa

Observed MW: 46 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ASCC1 Polyclonal Antibody DataSheet