ATP2B2 Polyclonal Antibody | G-AB-11350

ATP2B2 Polyclonal Antibody | G-AB-11350 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: ATP2B2, PMCA2, PMCA2a, PMCA2i

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 491

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ATP2B2 (NP_001674.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q01814

Santa Cruz:

Calculated MW: 127-136 kDa

Observed MW: 137 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ATP2B2 Polyclonal Antibody DataSheet