BAG3 Polyclonal Antibody | G-AB-08828
Gentaur Antibodies
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Gentaur Antibodies
BAG3 Polyclonal Antibody | G-AB-08828
- SKU:
- G-AB-08828
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
BAG3 Polyclonal Antibody | G-AB-08828 | Gentaur Antibodies
Overview: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism
Synonyms: BAG3, BAG-3, BIS, CAIR-1, MFM6
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 9531
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human BAG3 (NP_004272.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: O95817
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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