BAIAP2L1 Polyclonal Antibody | G-AB-08977

BAIAP2L1 Polyclonal Antibody | G-AB-08977 | Gentaur Antibodies

Overview: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in Signal Transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: BAIAP2L1, IRTKS

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 55971

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BAIAP2L1 (NP_061330.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UHR4

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BAIAP2L1 Polyclonal Antibody DataSheet