BAP1 Polyclonal Antibody | G-AB-11155

BAP1 Polyclonal Antibody | G-AB-11155 | Gentaur Antibodies

Overview: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS) , which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: BAP1, HUCEP-13, UCHL2, hucep-6

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8314

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BAP1 (NP_004647.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q92560

Santa Cruz:

Calculated MW: 80 kDa

Observed MW: 80 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BAP1 Polyclonal Antibody DataSheet