BBC3 Polyclonal Antibody | G-AB-09651

BBC3 Polyclonal Antibody | G-AB-09651 | Gentaur Antibodies

Overview: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: BBC3, JFY-1, JFY1, PUMA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 27113

Accession #:

Clonality:

Immunogen: A synthetic peptide of human BBC3 (NP_001120713.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q96PG8, Q9BXH1

Santa Cruz:

Calculated MW: 10 kDa/14 kDa/20 kDa/26 kDa

Observed MW: 20 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BBC3 Polyclonal Antibody DataSheet