BMPR1B Polyclonal Antibody | G-AB-09881

BMPR1B Polyclonal Antibody | G-AB-09881 | Gentaur Antibodies

Overview: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells

Synonyms: ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293, BMPR1B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 658

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BMPR1B (NP_001194.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O00238

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BMPR1B Polyclonal Antibody DataSheet