BMPR2 Polyclonal Antibody | G-AB-00160

BMPR2 Polyclonal Antibody | G-AB-00160 | Gentaur Antibodies

Overview: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction, Stem Cells

Synonyms: BMP type II receptor, BMP type-2 receptor, BMPR 2, BMPR 3, BMPR II, BMPR-2, BMPR-II, Bmpr2, BMPR2, BMPR3, BMPRII, BMR 2, BMR2, Bone morphogenetic protein receptor type 2, Bone morphogenetic protein receptor type II, Bone morphogenetic protein receptor type-2, Bone morphogenic protein receptor type II serine threonine kinase, BRK 3, BRK3, PPH 1, PPH1, Serine threonine kinase type II activin receptor like kinase, T ALK, TALK, Type II activin receptor like kinase

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Rat Bone morphogenetic protein receptor type-2 protein

Clone #:

Conjugation: Unconjugated

Swissprot: Q78EA7

Santa Cruz:

Calculated MW: 60 kDa

Observed MW: 60 kDa

Concentration: 2 mg/mL

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BMPR2 Polyclonal Antibody DataSheet