CAMLG Polyclonal Antibody | G-AB-08413

CAMLG Polyclonal Antibody | G-AB-08413 | Gentaur Antibodies

Overview: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium Signal Transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: CAMLG, CAML, GET2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 819

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CAMLG (NP_001736.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P49069

Santa Cruz:

Calculated MW: 32 kDa

Observed MW: 38 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CAMLG Polyclonal Antibody DataSheet