Caspase-14 Polyclonal Antibody | G-AB-11162

Caspase-14 Polyclonal Antibody | G-AB-11162 | Gentaur Antibodies

Overview: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: CASP14, ARCI12

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 23581

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human Caspase-14 (NP_036246.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P31944

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Caspase-14 Polyclonal Antibody DataSheet