Caspase-2 Polyclonal Antibody | G-AB-10798

Caspase-2 Polyclonal Antibody | G-AB-10798 | Gentaur Antibodies

Overview: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism

Synonyms: CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57, caspase-2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 835

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human Caspase-2 (NP_116764.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P42575

Santa Cruz:

Calculated MW: 10 kDa/34 kDa/50 kDa

Observed MW: 48 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Caspase-2 Polyclonal Antibody DataSheet