CAV1 Polyclonal Antibody | G-AB-01584

CAV1 Polyclonal Antibody | G-AB-01584 | Gentaur Antibodies

Overview: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags & Cell Markers

Synonyms: BSCL3, CAV, CAV1, CAV1, caveolae protein, 22 kD, caveolin 1 alpha isoform, caveolin 1 beta isoform, Caveolin 1 caveolae protein 22kDa, Caveolin-1, Caveolin1, cell growth-inhibiting protein 32, CGL3, LCCNS, MSTP085, OTTHUMP00000025031, PPH3, VIP 21, VIP21

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001744

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CAV1

Clone #:

Conjugation: Unconjugated

Swissprot: Q03135

Santa Cruz: sc-894/sc-7875

Calculated MW: 20 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CAV1 Polyclonal Antibody DataSheet