CBS Polyclonal Antibody | G-AB-08634

CBS Polyclonal Antibody | G-AB-08634 | Gentaur Antibodies

Overview: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD) , which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: CBS, HIP4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 875

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CBS (NP_000062.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P35520

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CBS Polyclonal Antibody DataSheet