CCDC112 Polyclonal Antibody | G-AB-04097

CCDC112 Polyclonal Antibody | G-AB-04097 | Gentaur Antibodies

Overview: CCDC112 (coiled-coil domain containing 112) , also known as MBC1 (mutated in bladder cancer 1) , is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6% of human genomic DNA and contains 181 million base pairs encoding around 1, 000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: MBC1, CC112, CCDC112, coiled coil domain containing 112, Coiled coil domain containing protein 112, Coiled-coil domain-containing protein 112, Mutated in bladder cancer 1, Mutated in bladder cancer protein 1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC031242

Clonality: Polyclonal

Immunogen: Fusion protein of human CCDC112

Clone #:

Conjugation: Unconjugated

Swissprot: Q8NEF3

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CCDC112 Polyclonal Antibody DataSheet