CD1B Polyclonal Antibody | G-AB-03598

CD1B Polyclonal Antibody | G-AB-03598 | Gentaur Antibodies

Overview: CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Immune System Organ Benign Neoplasm. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1C.This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: A1 domain, CD1, CD1A, CD1b, CD1b antigen, CD1B antigen b polypeptide, CD1b molecule, CD1B, Cortical thymocyte antigen CD1A, Cortical thymocyte antigen CD1B, Differentiation antigen CD1 alpha 3, hTa1 thymocyte antigen, Ly38, Ly38, T cell surface glycoprotein CD1a, MGC125990, MGC125991, R1, T-cell surface glycoprotein CD1b, T6/Leu6, Thymocite antigen CD1B

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001755

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CD1B

Clone #:

Conjugation: Unconjugated

Swissprot: P29016

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CD1B Polyclonal Antibody DataSheet