CD38 Polyclonal Antibody | G-AB-08358

CD38 Polyclonal Antibody | G-AB-08358 | Gentaur Antibodies

Overview: The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Immunology, Stem Cells

Synonyms: CD38, ADPRC 1, ADPRC1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 952

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CD38 (NP_001766.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P28907

Santa Cruz:

Calculated MW: 13 kDa/34 kDa

Observed MW: 42 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CD38 Polyclonal Antibody DataSheet