CD47 Polyclonal Antibody | G-AB-00322
Gentaur Antibodies
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Gentaur Antibodies
CD47 Polyclonal Antibody | G-AB-00322
- SKU:
- G-AB-00322
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Mouse
CD47 Polyclonal Antibody | G-AB-00322 | Gentaur Antibodies
Overview: CD47, also known as integrin-associated protein (IAP) , is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts a receptor for thrombospondin (THBS1) . It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-α (SIRPα) . Upon binding CD47, SIRPα initiates a signaling cascade that results in the inhibition of phagocytosis.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Immunology
Synonyms: Antigen identified by monoclonal antibody 1D8, Antigenic surface determinant protein OA3, CD 47, IAP, Integrin Associated Protein, Leukocyte surface antigen CD47, MER6, OA3, Protein MER6, Rh related antigen
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 16423
Accession #:
Clonality: Polyclonal
Immunogen: Recombinant Mouse Leukocyte surface antigen CD47 protein
Clone #:
Conjugation: Unconjugated
Swissprot: Q61735
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.3
Purification method: Antigen Affinity Purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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