CD68 Polyclonal Antibody | G-AB-10698

CD68 Polyclonal Antibody | G-AB-10698 | Gentaur Antibodies

Overview: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: CD68, GP110, LAMP4, SCARD1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 968

Accession #:

Clonality:

Immunogen: A synthetic peptide of human CD68

Clone #:

Conjugation: Unconjugated

Swissprot: P34810

Santa Cruz:

Calculated MW: 31 kDa/34 kDa/37 kDa

Observed MW: 100 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CD68 Polyclonal Antibody DataSheet