CDC45 Polyclonal Antibody | G-AB-09279

CDC45 Polyclonal Antibody | G-AB-09279 | Gentaur Antibodies

Overview: The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: CDC45, CDC45L, CDC45L2, MGORS7, PORC-PI-1, cdc45

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 8318

Accession #:

Clonality:

Immunogen: Recombinant protein of human CDC45

Clone #:

Conjugation: Unconjugated

Swissprot: O75419

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CDC45 Polyclonal Antibody DataSheet