CEACAM1 Polyclonal Antibody | G-AB-09615

CEACAM1 Polyclonal Antibody | G-AB-09615 | Gentaur Antibodies

Overview: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Category Type: Polyclonal Antibody

Research Areas: Tags & Cell Markers

Synonyms: CEACAM1, BGP, BGP1, BGPI

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 634

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CEACAM1 (NP_001192273.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P13688

Santa Cruz:

Calculated MW: 27 kDa/35-57 kDa

Observed MW: 120-130 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CEACAM1 Polyclonal Antibody DataSheet