CEBPA Polyclonal Antibody | G-AB-07249

CEBPA Polyclonal Antibody | G-AB-07249 | Gentaur Antibodies

Overview: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms: CEBPA, C/EBP-alpha, CEBP

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1050

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CEBPA (NP_004355.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P49715

Santa Cruz:

Calculated MW: 25 kDa/35 kDa/37 kDa/41 kDa

Observed MW: 41 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CEBPA Polyclonal Antibody DataSheet