CERS4 Polyclonal Antibody | G-AB-03222
Gentaur Antibodies
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Gentaur Antibodies
CERS4 Polyclonal Antibody | G-AB-03222
- SKU:
- G-AB-03222
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
CERS4 Polyclonal Antibody | G-AB-03222 | Gentaur Antibodies
Overview: The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction
Synonyms: ceramide synthase 4, CerS4, FLJ12089, LAG1 homolog ceramide synthase 4, LAG1 longevity assurance homolog 4, LAG1, S. cerevisiae, homolog of, 4, LASS 4, LASS4, LASS4 LAG1 homolog ceramide synthase 4, LASS4, TRAM homolog 1, Trh 1, Trh1
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_078828
Clonality: Polyclonal
Immunogen: Synthetic peptide of human CERS4
Clone #:
Conjugation: Unconjugated
Swissprot: Q9HA82
Santa Cruz: sc-65112/sc-65113
Calculated MW:
Observed MW:
Concentration: 0.8 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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