CKAP5 Polyclonal Antibody | G-AB-12255

CKAP5 Polyclonal Antibody | G-AB-12255 | Gentaur Antibodies

Overview: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: CKAP5, CHTOG, MSPS, TOG, TOGp, ch-TOG

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9793

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CKAP5 (NP_001008938.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q14008

Santa Cruz:

Calculated MW: 218 kDa/225 kDa/226 kDa

Observed MW: 250 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CKAP5 Polyclonal Antibody DataSheet