Claudin 1 Polyclonal Antibody | G-AB-05869

Claudin 1 Polyclonal Antibody | G-AB-05869 | Gentaur Antibodies

Overview: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: Claudin-1, Claudin1, CLD 1, CLD1, CLD1, CLDN 1, Cldn1, ILVASC, SEMP 1, SEMP1, Senescence associated epithelial membrane protein 1, Senescence associated epithelial membrane protein, Senescence-associated epithelial membrane protein

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from the C-terminal region of human Claudin-1

Clone #:

Conjugation: Unconjugated

Swissprot: O95832

Santa Cruz:

Calculated MW: 23 kDa

Observed MW: 22 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Claudin 1 Polyclonal Antibody DataSheet