CLDN12 Polyclonal Antibody | G-AB-06992

CLDN12 Polyclonal Antibody | G-AB-06992 | Gentaur Antibodies

Overview: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and Signal Transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: Claudin-12, Claudin12, CLD12, CLDN 12, CLDN12

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP036261

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CLDN12

Clone #:

Conjugation: Unconjugated

Swissprot: P56749

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CLDN12 Polyclonal Antibody DataSheet