Cleaved-CASP1 (D210) Polyclonal Antibody | G-AB-05848

Cleaved-CASP1 (D210) Polyclonal Antibody | G-AB-05848 | Gentaur Antibodies

Overview: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Can also promote apoptosis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism

Synonyms: CASP-1, CASP1, CASP1, Caspase 1, Caspase-1 subunit p10, ICE, IL-1 beta-converting enzyme, IL-1BC, IL1 beta converting enzyme, IL1B convertase, Interleukin 1 beta convertase, Interleukin 1B converting enzyme, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from the Internal region of human Caspase-1

Clone #:

Conjugation: Unconjugated

Swissprot: P29466

Santa Cruz:

Calculated MW: 45 kDa

Observed MW: 25 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Cleaved-CASP1 (D210) Polyclonal Antibody DataSheet