CMKLR1 Polyclonal Antibody | G-AB-09392

CMKLR1 Polyclonal Antibody | G-AB-09392 | Gentaur Antibodies

Overview: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2) , MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A) , as well as a primary HIV-1 strain (92UG024-2) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: CMKLR1, CHEMERINR, ChemR23, DEZ, RVER1

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1240

Accession #:

Clonality:

Immunogen: A synthetic peptide of human CMKLR1 (NP_001135815.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q99788

Santa Cruz:

Calculated MW: 42 kDa

Observed MW: 55 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CMKLR1 Polyclonal Antibody DataSheet