COL17A1 Polyclonal Antibody | G-AB-04872

COL17A1 Polyclonal Antibody | G-AB-04872 | Gentaur Antibodies

Overview: COL17A1 (Collagen Type XVII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL17A1 include Epidermolysis Bullosa, Junctional, Non-Herlitz Type and Epithelial Recurrent Erosion Dystrophy. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. An important paralog of this gene is COL6A1.This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: 180 kDa bullous pemphigoid antigen 2, Alpha 1 type XVII collagen, BA16H23.2, BP 180, BP180, BPA 2, BPAG 2, BPAG2, Bullous pemphigoid antigen 2, COL17A1, Collagen 17, Collagen alpha 1 XVII chain, Collagen alpha 1 (XVII) chain, Collagen alpha1 XVII chain, Collagen type XVII alpha 1, Collagen XVII alpha 1 polypeptide, CollagenXVII, Epidermolysis bullosa junctional localisata variant, FLJ60881, KIAA0204, LAD 1, LAD1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP000485

Clonality: Polyclonal

Immunogen: Synthetic peptide of human COL17A1

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UMD9

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.38 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

COL17A1 Polyclonal Antibody DataSheet