CREBZF Polyclonal Antibody | G-AB-05165

CREBZF Polyclonal Antibody | G-AB-05165 | Gentaur Antibodies

Overview: Host cell factor (HCF) is a cellular cofactor required for the activation of VP16 which expresses the herpes simplex virus immediate early gene. V16 binds to HCF through a 4-amino acid motif similar to the HCF binding domain of the basic leucine-zipper proteins Luman and Zhangfei (ZF) . Luman activates promoters containing cAMP or unfolded protein response elements (UPRE) . Zhangfei suppresses the transcriptional activity of Luman, but requires HCF binding which may target Luman and Zhangfei to a common location. Sequence analysis predicts that the deduced 272-amino acid Zhangfei protein has a negatively charged N terminus, a leucine zipper of 6 heptad leucine repeats separated by a conserved 6-amino acid spacer, a basic domain, and a bZIP region. It is also presumed that the N-terminal acidic region of Zhangfei is an activation domain.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: 1110034C16Rik, 6330417B10Rik, AI225749, AI606244, CREB/ATF bZIP transcription factor, Crebzf, FLJ94018, HCF-binding transcription factor Zhangfei, Host cell factor-binding transcription factor Zhangfei, LAZip, LAZipII, SHP-interacting leucine zipper protein, SMILE, ZF, ZHANG

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001034707

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CREBZF

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NS37

Santa Cruz:

Calculated MW: 37 kDa

Observed MW: Refer to figures

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CREBZF Polyclonal Antibody DataSheet