CST6 Polyclonal Antibody | G-AB-12045

CST6 Polyclonal Antibody | G-AB-12045 | Gentaur Antibodies

Overview: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins) , type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: CST6

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 1474

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CST6 (NP_001314.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q15828

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CST6 Polyclonal Antibody DataSheet