CTSC Polyclonal Antibody | G-AB-01619

CTSC Polyclonal Antibody | G-AB-01619 | Gentaur Antibodies

Overview: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: AI047818, CATC, CATC, Cathepsin C, Cathepsin J, CPPI, CTSC, Dipeptidyl peptidase 1, Dipeptidyl peptidase 1 light chain, Dipeptidyl peptidase I, Dipeptidyl peptidase I exclusion domain chain, Dipeptidyl peptidase I heavy chain, Dipeptidyl peptidase I light chain, Dipeptidyl transferase, DPP I, DPP-I, DPPI, EC 3.4.14.1, HMS, JP, JPD, MGC126959, PALS, PDON1, PLS

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001107645

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CTSC

Clone #:

Conjugation: Unconjugated

Swissprot: P53634

Santa Cruz: sc-5647/sc-5646/sc-13986

Calculated MW: 52 kDa

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CTSC Polyclonal Antibody DataSheet