CTSC Polyclonal Antibody | G-AB-12179

CTSC Polyclonal Antibody | G-AB-12179 | Gentaur Antibodies

Overview: This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: CTSC, CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1075

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CTSC (NP_001805.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: P53634

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CTSC Polyclonal Antibody DataSheet