CYP17A1 Polyclonal Antibody | G-AB-08513

CYP17A1 Polyclonal Antibody | G-AB-08513 | Gentaur Antibodies

Overview: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: CYP17A1, CPT7, CYP17, P450C17, S17AH, 20 lyase

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1586

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CYP17A1 (NP_000093.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P05093

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CYP17A1 Polyclonal Antibody DataSheet