DAB2 Polyclonal Antibody | G-AB-02418
Gentaur Antibodies
- SKU:
- G-AB-02418
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
DAB2 Polyclonal Antibody | G-AB-02418 | Gentaur Antibodies
Overview: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) , via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Synonyms: DAB 2, Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) , DAB2, Differentially expressed in ovarian cancer 2, Differentially expressed protein 2, Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein) , Disabled homolog 2, Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila) , Disabled homolog 2 mitogen responsive phosphoprotein, Disabled, Drosophila, homolog of, 2, DOC 2, DOC2, FLJ26626, Mitogen responsive phosphoprotein
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC003064
Clonality: Polyclonal
Immunogen: Recombinant protein of human DAB2
Clone #:
Conjugation: Unconjugated
Swissprot: P98082
Santa Cruz: sc-7828/sc-7832/sc-13982
Calculated MW: 82 kDa
Observed MW:
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.