DMAP1 Polyclonal Antibody | G-AB-10033

DMAP1 Polyclonal Antibody | G-AB-10033 | Gentaur Antibodies

Overview: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: DMAP1, DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 55929

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DMAP1 (NP_061973.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NPF5

Santa Cruz:

Calculated MW: 52 kDa

Observed MW: 60 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:1000-1:4000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DMAP1 Polyclonal Antibody DataSheet