DNM2 Polyclonal Antibody | G-AB-11924

DNM2 Polyclonal Antibody | G-AB-11924 | Gentaur Antibodies

Overview: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: DNM2, CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5, dynamin-2

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1785

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DNM2 (NP_004936.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P50570

Santa Cruz:

Calculated MW: 97 kDa/98 kDa

Observed MW: 125 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DNM2 Polyclonal Antibody DataSheet