DOK5 Polyclonal Antibody | G-AB-08414

DOK5 Polyclonal Antibody | G-AB-08414 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in Signal Transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: DOK5, C20orf180, IRS-6, IRS6

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 55816

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DOK5 (NP_060901.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9P104

Santa Cruz:

Calculated MW: 22 kDa/35 kDa

Observed MW: 30 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DOK5 Polyclonal Antibody DataSheet